VB6 could make apps that adapted themselves to window size, which was more flexible than different screen sizes.
It was no Apple's Cassowary, but so isn't HTML/CSS.
Some of the Wordpress, Drupal and Squarespace theme designers do the drag/drop GUI part where you can drop into the html, but it's more for graphic designers than programmers. I have watched a graphic designer be super productive with the WP Divi theme builder. But graphic designers are used to Adobe-like products with visual designers.
Yet things that were built, have been used.
And yet apparently they've never been good enough, because people keep asking for it.
Unfortunately the days of assuming everyone has a mouse, keyboard, and at least 4”x6” of screen to place a window on are long gone.