One thing I can't get over in regards to the sequel (Legacy) is how it changed the aesthetic of the computer world from nice bright neon on white and vivid purples to all black and neon blue or orange! Legacy is jam packed with CGI but it's still less visually interesting to look at (in my opinion) because of the lack of color. Not to mention it moves away from the "power to the users/believers" angle of the first film to try and take a philosophical stand on everything that amounts to meaning nothing.
Tron is a truly unique movie in everything it did, and my greatest sadness is that nothing that came after it has the same look and feel as the original. The closest we get is the world they had in Kingdom Hearts 2...