We could have universal Covid vaccines soon if we urgently reform the process

>> More broadly, I’m interested in getting things done quickly – especially things that are important for society.

>> We should lower the barrier for human clinical trials and use simpler endpoints. For many vaccine candidates, we could run human trials concurrent with primate trials (once basic safety data has been obtained).

What could go wrong...

How can you make human trials concurent with primate trials if you don't have the safety data in the first place...

>> Patrick Collison is a co-founder of Fast Grants and the CEO of Stripe.

Another guy who thinks that the human organism operates determinsticaly as a computer (which might be true assuming we'd fully understand and have the ability to observe and fully predict even all of the smallest molecular reactions in the body, which we don't even remotely have the technology to do so).

We hardly understand anything about the global-level interactions of the stuff you put in the body.

Move fast and break things works well in tech.

Not so much in real humans where the side effects of unknown unknowns can be fatal or permanently crippling.

Pro tip. This kind of person should never be involved in drug design unless it’s a follow on project to enter a known market. Google for phase 1 studies particularly of antibodies that ended up killing people. And there are some human conditions lacking animal models or working models (Alzheimer’s for example).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964774/

Drug research is time consuming because sometimes the dog dies or the candidate fails to do anything.