"We don't have many flying cars..." because of reasons that are completely out of the scope of this discussion. The airspace has a different set of rules and "vehicle operator" requirements in comparison to...the ground. Considering that many have trouble operating ground vehicles in a safe manner, i doubt that we're ever going to have manually controlled "flying cars" being a viable transportation option. And no, they wouldn't be as significant as the shift from ground travel to AIR, as we already have air travel options.
I didn't say that there is "an obvious demand", in fact i said quite the opposite, that not many people are going to want to live in the desert. When you're talking about the costs, do you mean the costs of desalination, transportation or both?