Until Windows drops 32-bit compatibility, VB6 apps will continue to run fine even if they do look f'ugly against todays UI design. In fact there's probably still a significant amount of industrial/heavy-commercial in-house applications written in VB still in use.
I can see a use case for TwinBASIC in maintaining these legacy apps, as the VB6 IDE no longer behaves itself under Windows 10/11. If it offers compilation to 64-bit (pseudo)code, then these apps will gain an extension on their usable life.