On the sites with more heavy tracking —- chegg comes to mind or some different clothing stores with lots of media, payment service scripts, and heavy ad tracking like tentree — the plug-ins definitely interfere to the point where I will sometimes use a second browser so that the website operates as intended. NoScript seems to be the culprit in most cases, and I suspect the interface doesn’t adequately display all the scripts attempting to load after the initial render.
I’ve had some trouble with sites which communicate between themselves too. (Airlines do this a lot).
All in all, I’d say my browsing experience is normal to the extent that I don’t do a lot of browsing to new sites. I’ve got a good running list for noscript, but any new sites with lots of dependencies and media to load usually requires a couple refreshed after an updated rule list.