E.g. if I'm hiring for a junior dev and get some self-taught person having done a couple of relevant online courses and so far managed to get a tech support role looking to become a programmer I'm often interested in talking to them.
On the other hand, I have seen cv's from senior enterprise/government engineers, 10 pages long, plastered all over with certs, titles, abbreviations, version numbers, iso standards, etc. and I have absolutely no idea what they actually did or achieved in their prior jobs even when googling a dozen terms. They might be great in the context they are working in, but they are from experience not a great fit for the context I'm hiring for.