Some of the more pleasant times are when I mix up ABV (already vaped weed) into edibles. Those I can get weak enough and with only the more stony compounds remaining where it can be pleasant, but it still turns me into a drooling idiot with absolutely horrific munchies.
It's like telling an alcoholic to try switching from vodka to tequila, because vodka makes you angry and depressed but tequila makes you a fun drunk. THC is THC, and any difference is psychosomatic.
> The research shows that genetically it is impossible to prove whether a cannabis plant is an Indica or Sativa. There is no difference in the genes.
> The overall chemical profile, like the genetics, shows no apparent difference between the labels.
Whether the Indica/Sativa marketing labels correlate with that chemical profile or not is besides the point. We know that different batches of the same strain can have different concentrations and ratios of all the of the relevant compounds because most legalized states require testing every batch. I don't know of any high quality research that studies how the subjective experience correlates with different doses and ratios but given that at least one of the most common compounds in cannabis is FDA approved to treat epilepsy (Epidiolex) and all the anecdotal evidence, it's really not a stretch to see how different strains produce different highs in different people.
If you think all weed produces the same effects then you first need to understand it's not all about thc.
First lesson Terpes: https://www.amazon.ca/Primary-Terpenes-Cannabis-Marijuana-In...
Next lessons: thc vs thca vs cbd