I don't see much point in going from one dynamic untyped language to another. Javascript and Python offer much of the same advantages and disadvantages, but having to deal with the overhead of running python code seems to just saddle it with tradeoffs for no real benefit. Learning one or the other is fairly easy too.
May as well write Javascript directly, as NPM is not short on packages if that's what you need. I see more value in going from higher level languages like ReScript, Purescript, Melange (Reasonml + Rescript compiler) to Javascript. You have to deal with things like code interop, strictness, overhead of compilation, but you at least gain in safety and succinctness.