For example, I bought a very large (15 gallon) vacuum chamber system directly from a US-based vendor. My use-case was to off-gas various slurries and compounds I use for my hobbies, such as casting molten aluminum. Although it was not directly mentioned on their e-commerce site, after a few follow-up marketing emails, I quickly realized they were geared towards solutions for businesses performing high-yield CBD extraction processes.
Ignoring all the politics of the related industries, I thought it was pretty interesting to find such a business by accident and that anyone with the right circumstances could potentially perform these processes with equipment available to general consumers - though I imagine there may be some chemicals that require a permit at the necessary concentrations.