Deno is only possible because V8 is so hyper-optimized. If you think about it, V8 has to compile/interpret and then run javascript code on the fly after downloading it in the browser. That's how good V8 is. That puts javascript in a unique position to enable something like Deno
So if there was a compiler/interpreter for another language that was close to being as good as V8, then something like this could exist for other languages.
Also, it looks like wasm works on Deno, so that gives some other languages.