Thank you for taking the time to write this out. My partner had a haemorrhage a number of years back, and has many of the symptoms you explain. The extreme tiredness doesn’t come on in the middle of the day, however at night it comes on very suddenly, as if a switch has been flicked. If you don’t mind me asking, how has your wife been with flying? My partner wasn’t fond of flying before, and we were advised to not fly for a number of years after.