Video game UIs do (almost) everything you just mentioned.

Accessibility: I'm not well versed on accessibility.

Power Use: mobile games are a thing. I wouldn't be surprised to find out that, on average, mobile games use less battery than electron apps (excluding Unity games. Unity games are the Electron Apps for video games).

cross-platform abstractions like I/O: video games run on more platforms than most apps with a larger variety of I/O and control types.

Regardless, that wasn't my point. My point is that video games are doing much, much more than most desktop apps could ever dream of doing in terms of pure work, and yet things like complex UIs and cross-platform deployments aren't considered difficult problems.