I loved Exapunks, TIS-100, Molek-Syntez and Opus Magnum. I still have not played Shenzhen I/O and I started Infinifactory yesterday, after learning about this last game. These games are all absolute gems. Especially TIS-100 was so simple with its three colors and its maybe four types of bleeps, and also quite hard, and yet it managed to somehow keep me in some sort of mood, to the point that there are only a handful of bonus puzzles left. That sequence merger puzzle pissed me off though :D
So this will be a collection of "smaller" games with different types of puzzles, but according to Zach, "some of these will be as large as TIS-100", which sounds impressive. For those wondering why this is the last game, Zach got a teaching job. I am sure his students will enjoy his classes a lot.