As for Cassandra itself, we were certainly quite sophisticated users. There's a decent chance you'd know the company in question. It's a fair point about the language: I'm not a fan of Java and it probably colours my opinion a little; I was speaking more from a philosophical standpoint about reducing the theoretical complexity of software to make it more deterministic & understandable (out of the tar pit and all that), more than to any specific deficiencies in Java that caused any actual issues for us, of which there were no direct examples I can recall. (Pathological GC did cause some occasional degradation, I suppose, though at best that's semi-specific to Java.)
I think most of the actual issues, from my on-call years, were as a result of stuff like: (as I mentioned) anticompaction and suchlike causing pathological performance; our own misconfiguration of things like asynchronous replication / bootstrapping (which once caused a very severe incident, as in 'endemic data corruption and loss' severity); application-layer issues from product engineers misconfiguring consistency, choosing poor keys for partitioning, constructing poor data models that require table scans, all the ordinary stuff for which Cassandra is at most very obliquely to blame.
Also, I agree it was stupid of us to use Cassandra in (what was) a very serious environment, in probably one of the most safety-critical sectors outside of medicine and rockets. We knew that. We did the same with several technologies. Literally, we had a diktat saying no engineers could mention it in blog posts. On reflection it's quite unfair to blame Cassandra for our decision - to a large extent, yeah, we were holding it very wrong. I would not have made that choice myself, at all.