The only Steam game in my library that still works now is Myst.

The list of Steam games that even supported macOS at all was already quite short, but now Portal, Portal 2, Team Fortress, the entire Half-Life series, and quite a few others will no longer run.

The switch to Apple silicon machines also makes running them in a VM tricky. Even though Windows supports running x86 code on Arm hardware, the mix of architectures inside the VM creates new problems, particularly for Steam.

Samsung Easy Document Creator scanner app.

With it, I could at least scan. Image Capture/Preview just produce invalid files. (Samsung M2070w). Now to scan I have to use Linux or Windows machine.

The most painful one for me: https://wxtoimgrestored.xyz

Tascam us-122mkII support was dropped. It is ancient, but it still works and there was a Windows 10 driver. I just got a cheaper Behringer uphoria that uses standard USB audio (or whatever) but loosing the Tascam was annoying.

If you're asking this question and not a Mac user I'll eat my Macbook.