Is Ruby on Rails Still Relevant in 2022?

I think the authors questions are not relavent at all. If you all you care about is the technology you use, fine.

But there is a reason for all this work. You are building a product. The questions should be related to building products.

- What is the size if your team? how much resource do you have? - Fast, Cheap or Good? (which two?) - Is it an unknown problem space? need to learn and iterate fast? - Market you sell to, high growth? medium? - Do you worry about scaling issues (eg. twitter) or more product issues - Do you want to use fancy tech or do you just want to build something?

Probably more questions like that would help answer what you should use.

Are Web frameworks still relevant in 2022?

You can get a lot done with the HTTP(S) handlers from stdlibs.