As to the broader issue, I agree with those here pointing out that indifference to human values is simply part of the nature of the universe. I wouldn't say that nature is inherently hostile, it's just indifferent. Survival of the fittest doesn't care about the feelings of those eliminated form the gene pool. The rules we code into computer systems are no more or less intractable to human values than the laws of physics that make our bodies work. I think this means that decision making on human affairs should fall to humans, which means all such decision are ultimately political ones. Crypto-anarchism can't do an end run around that.
Yet I think it's wrong to think of human values as purely a system we choose to impose on brute nature from outside it. We are part of nature. Our systems of values, and traits such as love and empathy are evolved behaviours. They were selected for by those same implacable laws of nature and survival of the fittest. So I don't see recognition of the implacability of nature as irretrievably nihilistic.