It turns out, more and more applications are locking the clipboard and holding onto the lock inappropriately. Enough that there's a particular telemetry watcher for this condition for MSFT to get an idea on who the guilty parties are.
Everyone has had it happen - I notice it when colleagues are in a rush and send me something they didn't mean to send (because their clipboard didn't update). I don't know who the guilty parties are (since that telemetry is encrypted, and can't be inspected), but I sure hope someone is knocking down some doors to address the problem.