The advice in these types of economic times from VCs etc. is to get to default-alive, e.g. a viable shot at cash flow positive before the money you have in the bank is gone.

While that view is understandable, can folks think of companies who did 20% type layoffs at the eve of bad times, e.g. 2001 or 2008, and then became market leaders, expanding as the market recovered?

I know Coinbase is not a typical startup given their IPO but they are a startup in other senses.