Please make your Turing complete game of life execute arbitrary Lisp code and you will have rescued the holy grail of computer language hacker nerdom here.
Native port of SectorLISP (https://justine.lol/sectorlisp/) to the Quest for Tetris processor (https://codegolf.stackexchange.com/questions/11880/build-a-w...), anybody?
SectorLISP is x86-specific, so this wouldn't just be neatly mushing existing things together, but I think the result could be very interesting nonetheless. I'm tempted to note that SectorLISP's tiny size could make this a reasonable one-shot/nerdsnipe-sized weekend project :D