Have you lost your ever-loving mind? Of course you're going to reboot. Bit rot improvements have only ever been incremental. To a first order approximation we've expanded from a day or two to a couple of weeks/months for general purpose computers (I argue that servers are not GP, and so their spectacular uptimes don't translate).
In thirty years, that's barely more than an order of magnitude improvement. You're gonna need a couple more orders than that before taking away the reboot option sounds anything like sanity. If you can keep a machine from shitting the bed for 2-3 times longer than the expected life of the hardware, then we can talk, but I'm not making any promises. Until then I'm gonna reboot this thing sometimes even if it's just placebo.