Expert: Monkeypox likely spread by sex at 2 raves in Europe
apnews.com
apnews.com
Explains what Monkeypox is, what the seriousness is, and how long it takes to recover. Most people recover in around a month without needed hospitalisation.
That is WAY more fatal than COVID
Rates are also different with better health care.
Not that monkeypox is awesome, mind you, but the fact remains the current circulating variant is not the one that has been fatal in up to 6% of cases.
(and also, that 6% is mostly children under 16. Again, not awesome, but the children dying in central africa to monkeypox, and children in the US/Europe/etc, have ... slightly different common health profiles )
Health care access is a factor for sure.
But there are also two main variants - one western africa, one central africa. The central african variant has high fatality rate in children/teenagers (1 in 10) The western african variant does not (1 in 100). All current cases are the latter, not the former.
(Not tons of data on health care factors involved in the two variants, but seems unlikely that the fatality difference is due mainly to health care).
We also have effective vaccines that are fully FDA approved. They can even be freeze dried :)
Production is always a factor, but if we needed to produce it fast, i'm sure it could be done.
Put another way - this seems ... unlikely to go the same way as COVID if it becomes a thing. We don't need to go do tons of research and studies and figure out how to fights it and etc. We just need to produce an already-approved effective vaccine.
Since than we have massively expanded testing to unprecedented levels, so the mortality estimates are now dramatically lower, both for cases and infections.
The two are not really comparable.
Monkeypox has two variants. One has a 10% fatality rate, which is not initial - it's been measured over decades. The other is less than 1%. What's spreading right now is derived from the less fatal variant.
So you're right that its not going to be 10% fatal, but it could have been, and it's not a new disease where we don't have good mortality rates, it's been here for decades.
It cannot be compare to fatality rates of Covid where everyone who gets a positive antigen test, regardless of the severity of symptoms, or even existence of symptoms is part of the denominator.
Of course the sample size is limited, but they seemed consistent with other mortality data.
Also, unlike in COVID, asymptomatic infection has never been demonstrated.
They are only testing clearly symptomatic patients. This cannot demonstrate asymptomatic infection if it exists.
Tracing also cannot demonstrate asymptomatic infection. It may be able to demonstrate asymptomatic transmission, though.
Today we define a Covid-19 case extremely liberally, which results in very low fatality rates. This is not comparable to the methods used for monkeypox in the early 2000s.
https://youtu.be/U7LgEHujoTU?t=710 (sorry for the Hebrew link)
If this is true, the 3% of 10% mortality rates are massively inflated.
> The trend in mortality reporting for COVID-19 has been typical for emerging infectious diseases. The case fatality rate (CFR) was reported to be 15% (six of 41 patients) in the initial period,1 but this estimate was calculated from a small cohort of hospitalised patients. Subsequently, with more data emerging, the CFR decreased to between 4·3% and 11·0%,2, 3 and later to 3·4%.4 The rate reported outside China in February was even lower (0·4%; two of 464).5
[1] https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
The name monkeypox originates from the initial discovery of the virus in monkeys in a Danish laboratory in 1958. The first human case was identified in a child in the Democratic Republic of the Congo in 1970
Are there known interactions with locals and monkeys? Are they consumed?edit: so there is consumption
monkey meat is common in bush meat stalls in the Democratic Republic of the Congo and Central Africa in general, with red-tailed and crowned guenons, baboons and agile mangabeys being the most commonMonkeys can get monkeypox, which means they're not the reservoir animal.
So presuming human-monkey is how the jump happened is starting off down the wrong path.
I agree with the rest of your comment, but is this part actually true? I would think an animal could serve as a reservoir as long as the disease isn't deadly. But I don't know and I'm happy to be corrected if wrong.
The obvious counter-example is herpes - where you periodically get symptoms and become infectious, but otherwise are not.
In the case of monkeypox though, as far as is currently known they are not major carriers of the disease - the name is just the animal it was first isolated in, since numerous other animals can be infected. [1]
That's not necessarily true. Many viruses are only pushed into dormancy by the immune system, and can come back and give you symptoms years later, at which point they can spread to other people. For example: Chickenpox, herpes, hiv.
" The patient reported that prior to his arrival in Singapore, he had attended a wedding in Nigeria, where he may have consumed bush meat, which could be a source of transmission of monkeypox virus."
https://www.moh.gov.sg/news-highlights/details/confirmed-imp...
Bush meat is a racist term concocted by European researchers.
"Bush meat" is simply meat obtained by trapping or hunting, as opposed to farming.
When Europeans or Americans hunt boar, ducks, wild pigs, dear etc is it called "bush meat"?
And if he may have consumed bush meat, was the bush meat raw or cooked?
Did he handle the raw meat himself?
Was there an outbreak among the guests at the wedding?
Are weddings the only place bush meat is available in Nigeria?
The kind of idiotic speculation Europeans engage in when it comes to Africa is totally of the chain.
They make all kinds of outlandish claims knowing that they don't have to justify them because in Africa anything goes.
The guy caught monkey pox period. No need to add any outlandish speculations to it.
I bet you also get outraged if someone refers to a 'blackboard' instead of a 'chalkboard'.
Did he claim to catch the animal live or handle the raw meat before it was cooked?
It is only in that case where the "bush" meat angle makes sense.
In this instance it's African and Asian speculation.
Your bias is showing.
Any infection from meat would come from uncooked meat, or handling the infected meat before it was cooked as cooking would kill any germs in it.
Is there some reason to believe that the meat he ate was uncooked?
He said he "may" have eaten some "bush" meat, he didn't say he handled the uncooked meat or animal.
It'd be called "game meat" or "wild meat". "The bush" is a synonymous term for the wild, and has neutral connotations.
> Bush meat is a racist term concocted by European researchers.
This paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122066/ would suggest that it was just a neutral translation of what people in Cameroon were calling it. Likely just "meat from the wild", which the English would have neutrally called "meat from the bush".
Why isn't the appropriate translation used?
The simple fact is it is a culturally loaded term suggesting that it is different and "unclean" in some way.
It is no different from the term "wet market" used in China to describe live animals or freshly killed meat.
Are the wholesale markets for fresh fish and fresh meat in Europe called wet markets?
my concern is then, is there a chance for this to become mutated and transmit? Say in a night club, stadium and concerts?
Anal sex is a risk factor for certain diseases, particularly HIV, but monkeypox does not require genital contact (or significant fluid transfer) for spread, so it's not clear if condoms would make much of a difference in this case.
Maybe the kind of sex affects the odds of STD transmission too, but I'd expect the number of dicerolls to be the primary factor and to be substantially higher among gay men in general.
TL;DR: Men are easy, some of them are gay too.
With that much risky behavior (with no protection), it is indeed a long series of dice rolls.
Sadly, it is very hard to have serious discussions about such topics nowadays, as one tends to get hit with the homophobia label.
Ride a jet ski wind up in the water.
If the tradeoff wasn't worth it they wouldn't do it.
The relevance really comes down do what question you are trying to answer.
If you want to know what factors have the biggest impact on reducing transmission, you will get one answer.
If you want to know what populations are at higher risk and what are they doing different, you will get another answer.
Not saying you are doing this, but by bringing it up, some people might think that’s what you are doing. I feel like I have seen it often enough that it is a fairly reasonable concern.
Is there a specific reason you are focusing on this issue, out of all of the thousands of issues you could choose to care about?
I am not focusing on it. I am just bringing it up on a thread where it seemed appropriate to. One person can care about more than just one issue at a time.
But the main difference for most in general is just that gay men have vastly more partners in a short period of time. You don’t really have a straight (or lesbian) equivalent of gay bathhouses.
> The virus enters the body primarily through broken skin (even if not visible), or the mucous membranes (eyes, nose, or mouth). Human-to-human transmission is thought to occur primarily through close contact with an infected subject. There are indications that transmission is occurring during sexual intercourse
as far as I know COVID is not transmitted primarily through broken skin, so it does seem more likely to be transmitted through sex.
You are technically correct about covid. However - and this was my point - if you have sex with someone with active, transmissible covid without substantial and properly fit PPE you are probably going to catch covid. It doesn't matter what type of sexual behavior you engage in, or what safer sex precautions that you take. That does not make covid an STI.
So like, you could get it from infected bedding if you had a cut, or it rubbed into your eye, or ....
Whether anything helps depends on whether it cuts down on most avenues above.
The sex part is mostly irrelevant, except that it is a very direct avenue to get it into your body vs "being coughed on" or "having cuts".
Chalk this one up to the media - someone identified that the current origination seems to have been a rave or two (or whatever), and that it can transmit sexually, and so now all the stories are about how it transmits by gay sex and blah blah blah. It's clickbait.
In that sense, lots of viruses transmit well by sex, monkeypox is not special or unique, nor is this likely to be the main transmission method as cases increase, even if it was the original transmission method. It has never been the main transmission mechanism of previous outbreaks.
I mean, heck, the fact that the media is focusing on the sex transmission helps guarantees it will transmit effectively the other ways - people think they are safe if they aren't having sex, but they are not!
The one part that isn't well-evaluated is the whole "how far do droplets travel" part. Right now the view of the CDC is that it requires prolonged face-to-face contact to get it that way because droplets can't travel very far (they are pretty heavy). The view of COVID started the same way.
It often ends up rarely that simple ;)
"Prostaglandin E2 in human semen given via anus during anal intercourse may cause an immune dysregulation in the male semen recipients; this immunosuppressive effect of prostaglandin E2 may be one of the underlying factors that stimulate AIDS-associated virus infection or that trigger the latent AIDS-associated virus. This hypothesis is supported by the following experimental results. Anal infusion of prostaglandin E2 or D2 into male rats reduced in vitro responses of T lymphocytes to phytohemagglutinin. However, the T-cell response of female rats was not reduced significantly by the anal infusion of seminal prostaglandins."
https://pubmed.ncbi.nlm.nih.gov/3458226/
"This method of alcohol consumption can be dangerous and even deadly because it leads to faster intoxication than drinking since the alcohol is absorbed directly into the bloodstream and bypasses the body's ability to reject the toxin by vomiting."
Both gay men and lesbian women prefer oral sex. This is well studied but not widely known because it goes against popular ideas of what counts as sex.
Anal sex occurs at these types of events but is not a dominating activity. People may engage in a wide variety of sexual activities. Some may not have sex at all. My guess is that sex was not a contributing factor, but rather close skin-to-skin contact among a large group of people wearing little more than underwear.
It's also possible the virus could have been spread through "breeding," a practice where one person will be penetrated by multiple people one-after-the-other much like a Tesla supercharger.
But get any group of half-naked people together in close quarters for hours and I am sure any type of virus like monkeypox will spread. As a gay person I would very much like to at least know the most probably theories.
It's very frustrating to see comments further down postulating that a lack of protection is the cause of the virus. Last time I checked, even sex with condoms involves skin contact.
Health authorities don't seem to have learned anything from COVID. The sooner information becomes available, even if the only information is "It could be this but we need to be sure," the better.
In the meantime, the LGBT community will have to deal with this kind of misinformation as well as not knowing how to protect themselves.
That's a rather unusual analogy. I don't recall ever penetrating a supercharger with anything, whether one-after-the-other or not! Is there some part of the joke that I'm missing?
yes and it is common for gays to have sex with way more partners, way more frequently, without protection, often using drugs. so it's a wonderful way to spread disease. look up the epidemiology of STDs in relation to MSM partner counts, it's eye-opening.
amazes me that people don't actually know the basic facts of this. i suppose this is what happens after two decades of politely not mentioning it -- what goes unsaid eventually goes unthought.
In a couple of reports I read yesterday of ex-Nigeria West African clade cases, which appears to be the same source and variant family for this Western outbreak, three cases started with pustules in the groin area before they gained a lot more coverage. From memory at least two of those cases were associated with handling rodents which are thought to be the animal reservoir for the disease.
Here we go again.
So I ask this person too, "what do you mean?"
Does circumcision actually have a non-neglible impact on the risk? From what I remember, it is insignificant, at best.
You can Google for other studies - the protective effect of circumcision is significant and large.
In most 1st world nations your assertion _may_ be true, but in Australia at least HIV is most prevalent in the needle sharing community.
It says:
New HIV infections have been reduced by 52% since the peak in 1997.
In 2020, around 1.5 million [1.0 million–2.0 million] people were newly infected with HIV, compared to 3.0 million [2.1 million–4.2 million] people in 1997.
Women and girls accounted for 50% of all new infections in 2020.
The assertion that 86% of new infections are in the gay community is falseHeck, the reason I'm on PrEP, and the reason virtually every other sexually active, non-long-term-monogamous gay man I know is also on PrEP, is because I know my risk of HIV infection is an order of magnitude more than straight men.
It's obviously different globally, where homophobia and prostitution mean different groups are vulnerable to HIV.
A quick search found that 86% of new HIV cases are among men who have sex with men. I couldn't find what % of the population is gay men, but all of LGBT makes up only 3-4% of the population.
There is practically zero risk of HIV to straight people who do not use iv drugs.
Your last sentence reminds me that COVID was going to be over by Christmas 2020...
https://www.gov.uk/government/news/new-hiv-diagnoses-in-gay-...
>A new report by Public Health England shows that for the first time the number of new HIV diagnoses in gay and bisexual men outnumber new diagnoses in heterosexual adults by only 100 cases.
So there's as many new HIV diagnoses among gay men as straight people, except gay men are only around 2% of the population. Notice you have to include all heterosexual people, not just the men, and it doesn't get up to just the cases among gay/bi men. The difference is staggering.
I'm sorry, but the real world data doesn't match the mythology around HIV. You are right about prostitutes though, I should've included that as a risk factor.
> gay men are only around 2% of the population
This is a dramatic underestimate by at least a factor of two. Only about 2% of boomers identify as gay, but it's five times that (or more!) if you ask younger generations. Unsurprisingly, younger folks have more sexual partners.
All of LGBT combined is only about 3-4% of the population. I will grant you that it's entirely possible 90% of LGBT is gay/bi men. I don't know.
I am however interested in social comportements in cats clowder/colonies (I'm from the countryside and i saw interesting comportements), and i am pretty sure i was researching information on homosexuality in cats due to homosexual comportements in two non-castrated cats from the clowder (we called it a gang). I found interesting articles about hormonal triggers during pregnancy (a bit disproven by homosexuality amongst penguins imho, but I'm not a researcher), and multiple studying homosexuality amongst social animals in multiple settings. I'm sure about the 4 to 5%, the rest is bad extrapolation and shouldn't be taken into account (i thought that was clear). Sorry if I ruffled your feathers.
Have a nice day!
> The cause of the disorder is unknown. Researchers call it A.I.D., for acquired immunodeficiency disease, or GRID, for gay-related immunodeficiency. It has been reported in 20 states and seven countries. [0]
[0]: https://www.nytimes.com/1982/05/11/science/new-homosexual-di...
It took about two years to figure out it was being spread sexually.
Makes you wonder why there are no lockdowns for the types of gay venues and events that have been identified as ground zero for the disease.
This is the objectively false messaging the parent comments are noting. There is nothing about this virus that makes gay men a uniquely potent vector for transmission. It's not how this virus is spreading, it's how it has spread in one case. It's a well-researched virus and the means that it propagates is well understood—nothing about the science requires gay people to be discriminated against.
If you wanted lockdowns, perhaps we should start with the sorts of places where people sit near each other for hours, eat and drink, and shake hands. We can start with churches.