I commute to SF on a weekly basis and stay in a hotel because it's cheaper than an apartment. And my bed gets made every day.
Edit: $65/day including tax * 13 days/month ~= $850. Allowing for holidays, vacation and occasional work from home. It's decent, better than Motel 6, more like Best Western. I got a good rate because I negotiated it years ago. It's outside SF itself, but I use Bart.