Any decent sized organization, even ones that don't have regulatory compliance to worry about, has to deal with the majority of things listed. My company has roughly 200 Macs in use, around 5% of the total endpoints in use. The admins who specialize in this have to worry primarily about patch management, application deployment, and security. Authentication is through AD, so any changes that might affect this have to be done carefully. And yes, printing is still a big deal.