This is about intestinal stem cells in specific.
And, of course, in mice.
(Still noteworthy if you are trying to understand why fasting seems to help with many different ailments.)
And, of course, in mice.
(Still noteworthy if you are trying to understand why fasting seems to help with many different ailments.)
Best I remember feeling in my adult life was after a 60 day fast. Not what I'd do today, or at least not the same way, but I highly recommend every healthy human fast for at least 7 days once every couple years.
The plural of anecdote is not evidence, YMMV, consult your doctor, I don't even play one on the internet, etc.
That being said, I'm currently on day 3 of an extended fast myself.
That one was super strict, no coffee, no tea, nothing.
EDIT - Also, this is _not_ how I would go about this now 5+ years later with more experience under my belt.
Estimating by weight loss my metabolism was still burning well over 2500kcal daily at the end of the fast.
An example:
A person with 14 % body fat and 74 kg body weight has around 10 kg fat. That is more than enough to go for about 30 days without any calorie intake.
If you have some fat (75% of westerners are heavily overweight or obese) you can easily fast on water only for weeks, of course you're not going to be able to exercise heavily every day or run a marathon. But if you're an overweight office worker with no other health issues you'll be just fine.
For anything over a week you probably should get medical assistance to keep an eye on vitamins and electrolytes, but you're not going to drop dead/unconscious/destroy your DNA
What's dangerous is starvation, aka fasting until your body starts giving up, but for the average westerner that's going to take a long time.
3) even if we assume in an ideal world, that the person who fast is able to supplement ALL the useful things and yet not take any external calories/glucose. This person would still reach a huge bioenergetic deficit/stress. Yes he will survive as you say, and might even be asymptomatic but nonetheless I would be very surprised if the biomarkers where doing Okay. Default bloodworks analysises are shit but if you command a proper analysis of your antioxidants ratio and of your bioenergetics biomarkers and apoptotic biomarkers you will see (unless I'm wrong which is very unlikely given my expertise) that the body is having a significantly accelerated aging/damage scheme. Which might not show symptoms before multiple decades later and even might not show symptoms at all in his life but statistically, there is a risk. Now he can mitigate some of those, by taking e.g. ALCAR + NAC daily for a year.
BTW the guy you linked died at 50 years old, which is not a performance.
for bioenergetics I don't remember the relevant ones although the manifestation is not only molecular, it can be observed (mitochondria respiration rate, uncoupling, etc) maybe this paper can show the relevant ones? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715336/
All I'm saying is that you were wrong. The human body can take much more than you explained in your first comment. You won't die nor fall unconscious and "5-7 days max" isn't anywhere close to the limit
I did not try to run quickly while fasting, but I did keep doing my 5km 3 times per week, and the gym. Anaerobic was hard and quickly tiring, but aerobic exercise wasn’t really any harder.
A friend did point out that my movement was “more economical” in general - I hardly lifted my feet while running or walking, and a few other things. But I didn’t feel more tired or more strained, except for unaerobics.
Glutathione possibly needs to be included as this will get low and Choline or Carnitine to remove the brain fog that occurred.
Averaged 18kg weight loss over the 18days, never felt so good in my life, like being a teenage male ramped up on Testosterone again, amazingly easy to fall asleep, excellent quality of sleep, vivid dreams which are recalled in the morning, not nightmares or anything like that. Foods which I dont like because of historical reasons smelt appealing and I wanted to eat them, no cravings for anything.
The only water I could really wanted, was the Scottish Highlands water, just didnt like Evian, S. Pellegrino, and the supermarket brands, and I wonder if highly filtered water ie dead water with no contaminants so its almost pure H2O would have been what I wanted, but they dont sell that in supermarkets AFAIK.
Ramadan is one of the fasts where you dont consume fluids during the day, and not consuming fluids will ramp up parts of your immune system which is why its important to drink fluid in order to not get angry. This could be in part because histamine is used by immune cells to move through tissues, but a personality side effect of high amounts is increased aggression. Anyone who supplements with histidine a precursor for histamine may also notice increased aggression. ie explosive rage, so be careful.
Totally agree, but maintaining brain function is my priority the ALCAR may also help considering its similar to choline.
During my fast, my sense of smell became super good but the smell of chlorine in the tap water was disgusting, I couldnt drink the stuff.
2-3 kg per week is a realistic number.
I just rolled into day four of a fast and the delta from two days ago is 3.72 kg.
Most of the weight you lose in the first 3 to 5 days of a fast isn't fat, its stuff in your gut and losing water as you draw down your glycogen stores.
But I’m only looking for documented examples, not extrapolated theory (which is what your first response seems to be), as — already in this thread - we have examples of 60 and 380 day cases with no observable I’ll effects (and I’ll add my own, multiple 15-25 days over the years, starting about 25 years ago — with doctor verified no I’ll effects a month later in most of them)
I watched my dad do 30-60 days every few years growing up. He always said how clear it made him mentally and the benefits to his health also was visible (until today he mountain-bikes across South East Asia during winter and he is in his late 70ies).
Longest I did was 40 days. Started out with 10 days a few years earlier which broke my misconceptions about if I would be able to do it. Especially the 40 days has been a healing journey for me both physically and mentally. It also gave me massive confidence about my body and taught me more about my limits than what decades of running did. I wouldn't do this long again because I lack the reserves today. But 10-20 days every few years is no issue.
Electrolyte supplementation on an extended fast is important, and I drank way _way_ too much water in the early weeks of that fast, which is also dangerous.
I read a lot of research last years about the subject, try search for 'fat inflammation'.
Fasting and a more plant based diet seem to reduce chronic inflammation.