It's heavily incomplete, but it runs "Celeste" on an ESP32. Some small games also run in the Raspberry Pico (RP2040), but it does not have enough RAM for medium-large games.
I've abandoned my Pico8 on RP2040 port though, a lot of games simply need more memory than there's available. There's this crazy guy: https://github.com/yocto-8/yocto-8/blob/main/doc/extmem.md that managed to get external RAM over SPI working (RP2040 does not support memory remapping)
On ESP32 with SPIRAM (/PSRAM) Pico8 is definitely achievable, and _most_ games will run at a playable frame rate, but some won't; as an example "Rockets!", does too many calculations per frame to run smoothly, and the Lua overhead starts showing so I'm exploring ideas like an optimizing compiler that can run off-console, etc.
I don't thing TIC-80 will be doable, the constraints are significantly more relaxed. A Pico8 framebuffer is 32KB; in TIC-80 it is 64KB (and this doubles with buffering/DMA) but most importantly, code is no longer something simple like Lua