Is the main idea here to be able to provide some of the benefits of a static binary (like a Go compiled binary)? Namely, you can keep this pyoxy binary with your project and then all of your custom code/dependencies/etc... are kept together in one single folder without relying on the system Python?
If so... I like it. Then the next step would be merging this binary with your code (plus dependencies) in one file, or maybe pyoxy plus an egg file? (or wheel? I can't keep track anymore). Seems like it would work for pure python dependencies pretty well, but would still have issues with dependencies that require compiling?