The experience I had with it the last time i tried it was that it was syntactically very similar to Clojure, but certain subtle differences with it. Close but not being precisely same as something else could often result in confusions.
On the other side I am quite torn about the decision. I quite liked the early releases of Hy where I could write a code that was much more familiar for me as a Clojure programmer. Still need to give a try to the new releases though.