> The canonical examples are low latency (with SLAs on the order of a disk or network I/O, so 10-100 microseconds) and applications that need to use bounded memory.

Well, in those cases extra developer time is cheaper than a more powerful computer!

Will you get ROI building a stereotypical web application with manual memory management? Doubtful.

Edit:

> GC shifts human work from development time to deployment / ops time.

I've never had to tune a garbage collector in deployment. I've heard of other people having to do it; but I've never heard of anyone saying, "yes, I'm so happy I built my website with C++."