Long-term risks of surgery: ‘It gives people’s brains a hard time’
theguardian.com
theguardian.com
It was very obvious in term of decline, my father had trouble with doing some tasks on his computer (when he never did before having been an early adopter and programming some educational software for schools in the 80s), he no longer could concentrate enough when reading and became more extreme in his politics (he went from voting from the parti socialiste and being mostly center left to being very left wing). He also had less control over his emotions and would sometimes explode in a rage unlike anything he had before.
He himself felt diminished mentally and that greatly bothered him during the last years of his life.
On my side, I've refused general anaesthesia as much as I can because it scares me deeply. When I was a kid, I had an operation under general anaesthesia and I woke up with a very strong asthma attack, completely unable to breathe. Reading this, it does give argument towards my stance to asking for local anaesthesia as much as possible.
In a general anesthesia you can't breath on your own so they stick a tube in your mouth. And it needs a special doctor (anesthesiologist) to perform the general anesthesia.
There was no anestesist (extra doc) present in the procedure, so I assumed it was no general anesthesia. But I dont know. Was it?
I don’t know the distinction between that and “general” anesthesia (they called this general), but I know there are different levels (and there was no need for breathing assistance at that level).
General anesthesia is a big deal both for the patient and for the doctors/hospital.
As an added bonus the doctor can show you anything they find on the screen and answer questions.
It wouldn't have occurred to me at all to ask them to put me under if there's a next time. And according to my SO, I'm rather pain intolerant.
If you're doing a biopsy I can imagine it's something else.
I've had two ablation's myself. After the 2nd one I suffered a stroke. It had no lasting effects I'm aware of, but that's just luck.
Heightened stroke risk is a well know is a side of ablation's. In the week or two after they are done tend to spin off clots, and that's when mine happened. However, to put that risk into perspective, stroke is also a well known side effect of the thing ablation's treat - arrhythmias. Unlike the risk from ablation's, the risk caused by arrhythmias goes on for life, and goes up as they get worse over time - which they almost inevitably do.
Anesthesia kills brain cells, but what does it mean? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119529
Heart lung bypass machines, ECMO systems, they all use non-pulsatile continuous flow pumps. These pumps do not have the same pressure curve and higher pressure pulses that the native circulation does. This causes blood to not make it all the way down to the capillaries, and therefore starves brain tissue that is fed by the smallest of the capillaries.
To solve this problem, a company I helped called Ventriflo has been working to build a pulsatile pump that can be used for both ECMO and cardiopulmonary bypass uses.
That's such a tiny, tiny, tiny percentage of surgeries and the risks being discussed are present without any heart-lung bypass being involved, ever.
That's not to say it's not an issue for people undergoing such a procedure, but it's just not what's being discussed here.
edit: Found the reference: https://www.frontiersin.org/articles/10.3389/fpsyt.2018.0075....
"More convincingly, a recent study demonstrated that open abdominal surgery under local anesthesia caused increases in hippocampal IL-6, TNFα, and memory impairments (71), suggesting that anesthesia per se is not necessary for the production of neuroinflammation and subsequent development of POCD."
"As seen in observational studies, a prospective randomized clinical trial comparing the use of general vs. spinal anesthesia in extracorporeal shock wave lithotripsy showed no significant difference in the incidence of POCD defined by a neurocognitive battery (142), suggesting that surgery and not anesthesia causes POCD."
So the possibility of anesthesia being the cause has not been ruled out by the studies you quote.
So yes, besides the inflammation, anesthetics are a problem.
Still, it's worth being able to breathe through my nose at night — and the benefits that brings (including to my dental health, as I was getting cavities multiple times a year despite me trying keeping my dental health impeccable; which now have stopped after a year post surgery).
Further, I'm willing to bet most people have no side effects from anesthesia, since most of the time they are only sedating you enough for you to be unconscious.
Maybe that will finally work to get my husband to discuss his painful-sounding snoring (with sudden stops) with a doctor and push to get sent for a sleep study!
What an ENT will likely do is scope your sinuses (costs a chunk of change, but pretty cool and informative), and send you home with a self-administered sleep study that may catch sleep apnea if it exists.
Essentially, get some 3M micropore tape, cut a 3-4cm long strip and place it on the middle of your lips. Half of the tape on the top lip, half on the bottom. If you’re really struggling to get airflow, try to get ‘breath right’ nasal strips and use those for a few weeks. You can re-use those if you’re careful, 2 nights usually. Good luck. Please reply if you have questions.
Also, this happens constantly and it's maddening, I'll be a few thoughts deep and can't backtrack to how I got here; I used to be able to unwind my whole train of thought.
I make a lot more typos and I also miss seeing a lot of them to correct them so they slip out in my writing, which used to be impeccable. There are even unique types of typos that I've started making -- if a word has repeated letters, I'll jump the letters between, so for instance "cognition" becomes "cognion". I never made this sort of typo before the procedure.
It's all gotten even worse since the pandemic which I've been told is stress-related, and absolutely nobody will take me seriously as a result.
What's worse, is the standard of diagnosability doesn't take into account how you used to be. So if you started off smart and now you're just sorta average, no problem here, why are you wasting our time? It's like if your Bugatti now accelerates like a Yugo, sorry, that's technically street-legal so according to this book there's nothing wrong with it. It has to perform worse than a Yugo before we can take a look. What a shitty mechanic, you know? But that's where medicine seems to be.
However...
I feel like this is how we got into the false causal relationship between autism and vaccines. Kids get a lot of vaccines in the first 4 years of life, and are diagnosed with autism then as well. So, you work backwards from a diagnosis and say, "oh the problems started a few weeks after the 3 year check-up, and they got shots, so the shots caused it!!" I would be worried we are doing the same here.
There is likely cognitive decline in men in their late 30s due to stress from work and kids, lack of sleep, reduced activity + weight gain, etc. We also get colonoscopies (or other procedures) around then as well. So, it is easy to say, "well I started having memory problems a few years ago, right around the time I had a hernia repair under general anesthesia, so they MUST be related."
No doubt some of that really is due to the virus, but it would be interesting to know for reference how many perfectly healthy people would be in that state just from going though the treatment.
Maybe for open heart surgery or brain surgery or some other extremely dangerous surgery where if you were to wake up the shock could kill you, but that would be overkill for a broken arm that needs pins to heal or for an appendectomy done with endoscopic tools.
Knocking you out and keeping you under would be more than enough for that.
Recreational, unsupervised self-administration of those drugs in recreational contexts is nothing like carefully measured and monitored administration in a hospital context.
An Anesthesiologist carefully administering calculated doses of Fentanyl to a fasted patient who is being directly monitored and surrounded by professionals capable of emergency resuscitation has almost nothing in common with an opioid addict taking a random dose of what they've been told is Fentanyl.
Don't get unnecessary surgeries, obviously, but don't confuse surgical intervention with drug abuse.
Nothing is actually safe by that logic. Dosage is the difference.
From that moment on though, my heart has never been the same. I developed an arrhythmia which they intially told me was due to the anesthesia and should go away within a week, but it has never gone away. Pre-surgery I had a stable idle heart rate - around 65 bpm - and now it fluctuates randomly between 50 and 115 every minute; again that's just sitting and doing nothing. My holter monitor tests showed many many episodes of both tachycardia and bradycardia as well as PVCs and PACs (palpitations).
I've been looking into "awake" surgeries lately for my back, so hopefully that will be a reasonable option for most things in the near future.
It really is a crapshoot and/or an art. It’s not surprising that people are having long term cognitive complications from having our brains forcefully shut down.
I’m going to need every medical professional to define “young” at the beginning of their articles, abstracts and research papers from now on.
It was about 2 years ago today when I realized this isnt the same word or context as the general population and the communication skills of that entire industry is inadequate for ever saying anything to the public.
Why is it so hard? I would think a citicholine supplement could be administered to examine this hypothesis, unless the hypothesis is that utilization of choline is somehow blocked.
This is major surgery. Be prepared for possible consequences. [https://www.medicalprotection.org/southafrica/casebook/caseb...]
Indeed and it's a very harmful narrative even without detransitioner concerns. Once you've had your breasts lopped off, or womb removed, or - if male - penis and scrotum fashioned into a pelvic cavity, no amount of further surgery can reverse this. Those organs are gone permanently.
https://www.youtube.com/watch?v=ZKMBWOBbyws
You seriously want to ponder whether you should get any surgery at all...
Relatedly: had ~15 surgeries before the age of seven back in the 90's when there was zero notion of these nuances, and there's not a small part of me that wants to slide in a mention of "Hey, a lot of this could be second-order effects of medical/ICU CPTSD". Typically the kiddos coming in for multiple surgeries already have a few major medical issues - and so bouncing back from "multiple" operations paints a lot different picture than just one clean-and-done one.
Your personal risks could be much higher or lower, and quantifying them is basically impossible. It only makes sense to use the "average" risk level for reasoning if the sampled population is particularly representative of you, which is vanishingly unlikely due to the "curse of dimensionality".
It makes a lot of sense to decide public policy of how driving should be managed based on those statistics, but is hilariously inappropriate to base your decision to get in a car and drive based on them.
Driving and surgery both involve a lot of risks you can do nothing about, making statistics (selected for your demographic, of course) the most you can know. Statistics are not a good way to predict whether one's self will buy a red shirt or a green shirt (when you can know exactly what you will do because you are deciding), but you have no say in whether or not your anesthesiologist will guess the right dose or whether your surgeon will put the sutures in exactly the right positions to stop a post-op bleed. The same goes for most accidents, which are called "accidents" because culpable negligence is actually pretty rare.
It's a problem of different goals. In the variants of "Maximize net good/minimize net harm" frequentist statistics are appropriate to reason with. From a individual "maximize my personal quality of life" perspective, I am likely member to many intersectional groups and complexities that render that statistical reasoning meaningless. You can only generalize the results of a study to those represented by it's sampling and the cold hard reality is that a nontrivial amount of people are not represented.
Public health reasoning is entirely self consistent and rational given it's goals (minus perversions due to capitalism and rent seeking).
The problem is that it is actively hostile to most people who are disabled, a minority, or dealing with any long-tail health problem.
Some successes (Heart surgery helped with chronic migraine pain). I'm currently turning off large swaths of my immune system in hopes that Celiac, Crohn's and Psoriasis get better.
https://www.denverpost.com/2014/06/16/attitude-can-play-sign...
It can be very easy to fall into a depressive spiral. Your outlook on the situation can matter.