Pfizer scientists transformed an old drug lead into a Covid-19 antiviral

cen.acs.org

6 points·FatalLogic··4 comments

Pfizer no longer have trust. For anything. Just read the documents they were forced to release this year (rather than 75 years in the future) - you figure out pretty quick why they wanted it covered up for 75 years. It's horrific.

I’m not following. Could you link to the documents you’re referring to?

Entrepreneurs and startuppers. That's the reason why if a big disruption happens you and your company should stay away from ground zero.

Even if you do a hell of a job cleaning up and saving lives, armchair Quarterbacks will hate you, and the people whose quality of life you improve will want your head.

Pfizer and Moderna delivered a 125 mph strike in the middle of the plate.

MRNA platforms such as the one of the COVID vaccines could be the reason why having to go through chemotherapy at some point in our lives maybe not a grim reality to just accept and swallow.

Billons of people took the vaccine, but of course they'll all drop dead at any moment /s

'Hacking' an intravenous drug to make it work as an oral drug: One key part of the chemists’ strategy was to eliminate some of the hydrogen bond donors that keep PF-00835231 in the gut. If a particular hydrogen bond is critical to making the compound bind to the protease, it had to stay in the molecule. “We were looking for hydrogen bonds that we could get rid of without losing antiviral potency.”

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