Ask HN: How to deal with challenges that come with pursuing your own vision?

Founders, independent researchers, etc., how do you deal with all the challenges that often come with pursuing your own unique vision?

It's a very big question, but here are some of the things I've struggled with myself, or can imagine happening:

- general lack of guidance and trying to figure out everything yourself

- self-doubt and dealing with criticisms, failures, disappointment

- staying motivated and maintaining progress

- staying true to your vision, while being open-minded to feedback

- navigating big shifts in direction

- feeling isolated/alone because no one else understands your vision