I’d imagine there are quite a few studies that say the opposite? Is this study special? Larger sample size?
I’d be curious to look at biological age markers, inflammation, autophagy, maybe improvements in insulin response, cardiovascular health in the long term.
"Results of analyses of waist circumferences, BMI, body fat, body lean mass, blood pressure, and metabolic risk factors were consistent with the results of the primary outcome. In addition, there were no substantial differences between the groups in the numbers of adverse events."
So weight loss was the primary target, with some ancillary metrics. But it was only a 12-month baseline, which may not show longer-term benefits. And it didn't include any effort to assess things like inflammation or immune system robustness, which personally are the only reasons I do intermittent fasting.
>The studies to date in humans are limited in size and duration, and the effectiveness and acceptability of TRE in the general population remains unclear.
Skimming this new paper and it seems to me that the sample size is about twice as big as previous studies.
[0] https://www.sciencedirect.com/science/article/pii/S258900422...