Usage is what matters. Standards documents only have value as long as people follow them; once enough people deviate, they cease to have meaning. This is thoroughly the case with a lot of stuff pertaining to email: if you want to parse arbitrary emails, for example, the relevant MIME RFCs are altogether insufficient, because too many people have done it incorrectly
de jure, often to the point where it’s no longer incorrect
de facto because everyone supports the deviation. (This is a deviation from spec in the direction of
permission.)
By hearsay alone, I say: comments and quoted strings in email addresses are, de facto, more or less dead. Comments especially, which were intended just as a compatibility measure for stuff from over forty years ago (when this was being developed organically, before there was any real spec). Most software whose direct business is email (that is, MUAs and MTAs) will more or less support them for historical reasons, but newer MUAs are likely not to support them in full (again especially comments), and I suspect the considerable majority of other software that deals in email addresses won’t support one or both of them. (This is a deviation from spec in the direction of restriction.)