There's a great tech demo a dev did a year or two ago showcasing GPT-3, speech-to-text, and text-to-speech to have random NPCs in a VR open world respond to anything the guy said if he walked up to them and talked to them.
Procedural generation has taken on almost a "dirty word" reputation in the past few years in gaming, but as AI continues to allow for exponential variety at increasingly high quality, it's going to enable some truly mind boggling experiences.
Expect to see MMO models (subscription fee and server-oriented) but for single-player instanced worlds dynamically generated around your interactions in them.
I can't wait to have a party of friends to go on epic adventures with that are all just AIs I picked up across a world along the way.
Less than 20 years away, and possibly even less than 10.