For me the breakthrough was when I realized that the colors I think I see in the world are all lies. Try this: look at something near you that's a uniform color. Looks like one color, right? Wrong! Light hits the object, and bounces off in a million different ways depending on physics. Your brain interprets these light rays as a single composite color for each object, but it's not the physical truth - it's just a simplification to deal with overwhelming detail. If you want proof of this, just look at what a digital camera sees. Pixels that the brain would consider the same color... aren't.
A big part of the artist's journey, perhaps the main part, is in developing the ability to break through the brain's natural conceptual abstraction layer and see the world much closer to the sensory raw data that normally goes unnoticed. Ironically, the better an artist manages to reproduce these low-level details, the more their work will seem obvious and like something anyone could do!