sure not a usa-ism, but just bad software. We'd probably say the A6 or the A6thou or something short. or the 21-79. whatever's shortest and not a mouthful.
true 'mericans don't even know how to pronounce-out numbers that bigly
here in california there is this delightful local custom to give the freeway some random place name that changes every two miles, but give all the signs a number. or vice versa.
so it sounds like: "turn north on the rancho-el-coronado-pacifico-jackson expressway" which means turn "physically east on the 610" because it's actually north-south, but run's east-west "logically".
then for extra fun, add state highway numbers that overlap the us freeway numbers and use lots of proper nouns. as in "a crash occurred at the interchange of the northbound 415 and the 188 at the south 67 jason plotz memorial parkway on the escobar-de-los-muertos exit headed eastbound". i don't even know what i just said, but at least twenty commuters reading this just rerouted to avoid this mess.