Anti-intellectualism aside, they still interrupted an amazing talk without adding any value. An actor's way of dominating the stage even when it's not your turn. A bit rude and unnecessary.
"OH, oh I'm sorry, but this is abuse."
"Oh, I see, well, that explains it."
"Ah yes, you want room 12A, Just along the corridor."
Honestly though, if people were enjoying them, I don't think it's any less rude. It says more to me about the anti-intellectualism mentioned earlier. Reminds me of the Diesel campaign surrounding the word "Stupid".
I don't know, I think you can nail this kind of repartee and it's funny and makes things flow - which stops the day from getting boring and stiff. But I hate it when it's not quite right. Kinda like the MC at a gig who tries to make bad jokes and ends up being super awkward.