I have been using mutagen for few years. It has been a life saver.
I use it mostly to work on remote projects, mostly for development, rarely working on prod. So there I have my projects on some cloud linux instances and I work locally on windows, mostly phpstorm.
Having the webserver in the cloud and doing the heavy lifting is quite nice, especially if you work with phpstorm, which can be a resource monster for bigger projects, and working on remote projects with phpstorm built in sftp / file sync is a huge pain in the ass, really slow.
With mutagen it feels almost like I work locally. Thanks to the developer for this cool tool!