At the time SQLightning greatly improved SQLite performance but due to LMDB's requirement to have keys fit in 2/3 of a page it wasn't really useful as a general purpose replacement of SQLite's internal b-tree implementation.
EDIT: It looks like SQLightning got adopted and has been worked on by the SQLite team under the name LumoSQL. Here's the project's readme: https://lumosql.org/src/lumosql/doc/trunk/README.md which contains at the end "A Brief History of LumoSQL"