Blocking those who like a tweet seems excessive. Plenty of bad hits — people who use likes as bookmarks, etc. What would be really nice is to be able to group block by profile content, or if they were simultaneously followed by five accounts of your choosing. Some fine-grained blocking like that would be nice; it would also be nice if muted words & phrases would also apply to search results — I've seen too many sneak through, especially when attached to hashtags.