> This is not just an academic exercise. This type of technological progress has the potential to transform personal genomics—where individual genomes can be used to inform health decisions.

I don’t think genetic interpretation is yet or will soon be at a point where a significant number of people (say, greater than a half of a percent) can benefit structural genome information, much less have the field be transformed. Heck, we have a hard enough time resolving the impact of single nucleotide variants in coding regions. While large copy number variants have the potential for significant impacts, for the most part we can resolve these pretty well to the necessary level of detail with current tech.