I use Clojure every day at work and it's my favorite dynamic functional language. That said, I think in large projects like the one I'm working in, a statically typed language would've been better. I know Clojure has spec and other similar libraries but it's just not a replacement for static typing.

I love Clojure and would use it for small projects if given the chance but I think there are diminishing returns when you scale up, specially if you deal with a complex data structures which get encoded and decoded to JSON (messes up things like keywords).