The case that always interested me is the service that can really fit on one machine. Machines are truly gigantic in terms of memory and disk. Heck, I worked at BrickLink which ran on two beefy machines that serviced 300k active users (SQL Server is actually quite good, it turns out). (A single beefy server is a really great place to start iterating on application design! PostgreSQL + Spring Boot (+ React) is a pretty sweet stack, for example. By keeping it simple, there are so many tools you just don't need anymore, because their purpose is to recombine things you never chose to split. I can't imagine why you'd need more than 16 cores, 128G of RAM and 10T of storage to prove out an ordinary SaaS. That is a ferocious amount of resources.)