First and last author both work for a company that sells saffron products for medicinal use.
At least they state this caveat themselves "Larger clinical trials, conducted by research teams outside of Iran, with long-term follow-ups are needed before firm conclusions can be made regarding saffron's efficacy and safety for treating depressive symptoms."
This is not news worthy at all.
Avicenna described saffron's anti-depressant effects literally a thousand years ago, in a textbook that remained the standard medical dogma even in the western universities until 17th century.
a thousand years long track record, this is definitely worth investigating deeper.
I haven't read the paper but the absolute best outcome would be that they list all the studies they evaluate for inclusion (which is most of the work, finding and evaluating) so that others could perform similar analyses with a big head start.