But I like the concept for areas such as schools etc., because it makes it possible to try a bunch of different things very fast.
In terms of "serious use" I think that depends on what you mean by "serious". E.g. my hone automation setup is not static, because I keep finding new little things I want to tweak, and often the ready-made solution lack options I'd like to have unless I'm willing to spend time tracking down very specific modules. My time is valuable to me - I'd happily pay extra for a modular system where I know if something is lacking a button for something I want I can literally just plug one in instead of having to search all over for a different model of something.
Of course this will not replace mass market "close enough" solutions.
But I think there are still more than enough people who want to tinker but don't want to have to whip out a soldering iron.
Things like a single dimmer etc. is not the problem, because for simple stuff like that there are plenty of off the shelf options.
The issue is anything that deviates from what manufacturers expect. And yes, I'd be happy to use a lot like that for that even at a quite high cost because the existing options to do it cleanly without a self build are also expensive.
But I am not sure about the rest.
And what you don't see in demos like this are the practical limitations that the demo avoids. I didn't watch all the way to the end but I had questions about how the device communicates its limitations and handles situations where, for example, it cannot supply enough power.
EDIT: Though that does make a key weakness the fact that there doesn't appear to be any provisioning for locking down the blocks more aggressively to the board.
I'm betting that it will be cost-prohibitive to have this device as a permanent fixture for any one application outside outside of the sorts of things an rPi4 already does (Home Assistant server, etc). I don't think anyone is going to use it to control an LED with a slider, but for prototyping that sort of thing it has endless possibilities.
Hats off to Anil for the huge amount of work he put into this project.