Mexico City, at least in the central parts, has an interesting layout. Busy avenues roughly 1km apart grid the neighborhoods. Inside those squares most of the streets are one-way and low speed. You can walk in almost any direction and find a bus or subway station in 8 minutes. And of course they mix residential commercial and light industrial freely. It’s not unusual to find a small furniture maker next to a restaurant below an apartment building. They don’t ban cars and the “blocks” are larger, but it seems to work.