In practice I'm not sure there would be much duplication. Even for tools using the same libraries they are very often using different versions.
===========================================
no dedupe: 16.0 GB (17228518418 B)
dedupe: 11.7 GB (12594871766 B)
singlelet: 8.1 GB (8677649129 B)
orphan: 1.8 GB (1889889290 B)
===========================================
deduplicated size ratio: 73.10
singlelet space usage: 68.90
singlelet file ratio: 63.56
orphan space usage: 15.01
orphan file ratio: 2.63