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Probably, I know I distrust most of the food "science".

When I stuck to "food" pyramid, I was the most unhealthy, overweight, and unhappy I've ever been. When I basically switched to high fat, high protein, and lowish carbs,I got healthier and more importantly my hormone profile went back to normal and I wasn't depressed anymore.

It's astounding what lies the government pushes around food, and how damaging it can be to your life!

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The thing with food science is that not every human is the same and people react differently to different things. Some people may thrive on a high fat diet, other might tolerate or even need more carbs, it really depends and isn't black and white. Thats why it's important to look at the sample size of studies among other factors.

Is there some evidence that humans really react that differently all else being equal?

Literally anything that can affect our bodies might be a confounding factor: sleep; water intake; type, frequency, duration, and difficulty of exercise; sunlight exposure; climate (average temperature, humidity, temperature swings, atmospheric salinity); elevation; latitude, etc...

Celiac, lactose intolerance, fructose malabsorption, migraines... there are plenty of variations that cause people to handle foods differently.

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